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Invitrogen™ CYR61 Recombinant Rabbit Monoclonal Antibody (HL2144)
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Catalog No. FEMA550399
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100 μL
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FEMA550399 100 μL
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Catalog No. FEMA550399 Supplier Invitrogen™ Supplier No. MA550399
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Description

Rabbit Recombinant Monoclonal Antibody

CYR61 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

CYR61 is a secreted heparin binding protein, encoded by a growth factor inducible immediate-early gene that associates with the extracellular matrix and connective tissue. CYR61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse CYR61 homolog, Fisp12. As an angiogenic inducer, CYR61 binds to the cell surface receptor integrin alphavbeta3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of CYR61 is elevated during vessel growth, wound healing and chondrocyte differentiation. CYR61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYR61
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone HL2144
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CCN1
Gene Accession No. O00622, P18406, Q9ES72
Gene Alias 3CH61; AI325051; CCN family member 1; CCN1; cellular communication network factor 1; Cyr61; cysteine rich angiogenic inducer 61; cysteine rich protein 61; cysteine-rich angiogenic inducer 61; cysteine-rich heparin-binding protein 61; cysteine-rich, angiogenic inducer, 61; cysteine-rich, anigogenic inducer, 61; GIG1; IBP-10; IGF-binding protein 10; IGFBP10; IGFBP-10; insulin-like growth factor binding protein 10; insulin-like growth factor-binding protein 10; intermediate early; protein CYR61; Protein GIG1
Gene Symbols CCN1
Host Species Rabbit
Immunogen Recombinant fragment of human CYR61.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16007, 3491, 83476
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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