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Invitrogen™ CYSLTR1 Polyclonal Antibody
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Catalog No. PIPA528735
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100 μL
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PIPA528735 100 μL
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Catalog No. PIPA528735 Supplier Invitrogen™ Supplier No. PA528735
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, HeLaS3, HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYSLTR1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene CYSLTR1
Gene Accession No. Q9Y271
Gene Alias BB147369; CysLT 1; CysLT(1); Cyslt1; CysLT1 receptor; Cys-LT1 receptor; Cyslt1r; CYSLTR; Cysltr1; cysteinyl leukotriene 1 receptor short isoform; cysteinyl leukotriene D4 receptor; Cysteinyl leukotriene receptor 1; G-protein coupled receptor HG55; HG55; HMTMF81; LTD4 receptor; LTD4R; MGC46139
Gene Symbols CYSLTR1
Host Species Rabbit
Immunogen Synthetic peptide encompassing a sequence within the Extracellular domain of human CysLT 1 Receptor. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10800
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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