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Invitrogen™ CYSLTR1 Polyclonal Antibody
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Catalog No. PIPA595939
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100 μL
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PIPA595939 100 μL
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Catalog No. PIPA595939 Supplier Invitrogen™ Supplier No. PA595939
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MDETGNLTVS SATCHDTIDD FRNQVYSTLY SMISVVGFFG NGFVLYVLIK TYHKKSAFQV YMINLAVADL LCVCTLPLRV VYYVHKGIWL FGDFLCRLST; Positive Samples: U-937, A-549, BxPC-3, HeLa, Mouse kidney; Cellular Location: Cell membrane, Multi-pass membrane protein.

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYSLTR1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.04 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene CYSLTR1
Gene Accession No. Q99JA4, Q9Y271
Gene Alias BB147369; CysLT 1; CysLT(1); Cyslt1; CysLT1 receptor; Cys-LT1 receptor; Cyslt1r; CYSLTR; Cysltr1; cysteinyl leukotriene 1 receptor short isoform; cysteinyl leukotriene D4 receptor; Cysteinyl leukotriene receptor 1; G-protein coupled receptor HG55; HG55; HMTMF81; LTD4 receptor; LTD4R; MGC46139
Gene Symbols CYSLTR1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CYSLTR1 (NP_0066301).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10800, 58861
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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