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Invitrogen™ Cystatin 8 Polyclonal Antibody
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Catalog No. PIPA5103769
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PIPA5103769 100 μL
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Catalog No. PIPA5103769 Supplier Invitrogen™ Supplier No. PA5103769
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CST8.

The cystatin superfamily is a well-established family of cysteine protease inhibitors. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, while some also inhibit legumain family enzymes. The CRES (cystatin-related epididymal spermatogenic) protein defines a new subgroup in the family 2 cystatins of the cystatin superfamily. CRES proteins lack two of the three consensus sites necessary for the cystatin inhibition of C1 cysteine proteases. They are also preferentially expressed in postmeiotic germ cells, the proximal caput epididymidis, and anterior pituitary gonadotrophs. Therefore, CRES proteins may perform unique and tissue-specific functions in the reproductive and neuroendocrine systems. As a member of the CRES subfamily, Cystatin 8 is a 142 amino acid protein that is expressed in the proximal caput region of the epididymis, where it performs a specialized role during sperm development and maturation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cystatin 8
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CST8
Gene Accession No. O60676, P32766
Gene Alias CRES; CST 8; CST8; Cst-rs1; CTES5; cystatin 8; cystatin 8 (cystatin-related epididymal specific); cystatin 8 (cystatin-related epididymal spermatogenic); cystatin-8; Cystatin-related epididymal spermatogenic protein; cystatin-related epididymal-specific protein
Gene Symbols CST8
Host Species Rabbit
Immunogen A synthesized peptide derived from human CST8(Accession O60676), corresponding to amino acid residues L81-E131.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10047, 13012
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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