Invitrogen™ Cystatin A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551502

Catalog No. PIPA551502

Description

Immunogen sequence: IPGGLSEAKP ATPEIQEIVD KVKPQLEEKT NETYGKLEAV QYKTQVVAGT NYYIKVRAGD NKYMHLKVFK SLPGQNEDLV Highest antigen sequence identity to the following orthologs: Mouse - 60%, Rat - 65%.

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

Specifications

• Antigen: Cystatin A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CSTA
• Gene Alias: AREI; Csta; Csta1; cystatin A; cystatin A (stefin A); cystatin A1; cystatin AS; cystatin-A; Cystatin-A, N-terminally processed; Cystatin-A1; Cystatin-AS; PSS4; Stefin A; stefin-A; STF1; STFA
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1475
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P01040
• Gene Symbols: CSTA
• Immunogen: Recombinant protein corresponding to Human Cystatin A. Recombinant protein control fragment (Product #RP-93681).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov