Invitrogen™ Cystatin D Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547987

Catalog No. PIPA547987

Description

In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human (rh) Cystatin C, rhCystatin SN, and rhCystatin S is observed and less than 1% cross-reactivity with rhCystatin E/M and rhFetuin A is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity.

Specifications

• Antigen: Cystatin D
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CST5
• Gene Alias: CST5; CSTD; cystatin 5; cystatin D; cystatin-5; Cystatin-D; cysteine-proteinase inhibitor; MGC71922
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1473
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Neutralization, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P28325
• Gene Symbols: CST5
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Cystatin D Thr29-Val142.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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