Invitrogen™ Cystatin S Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596939

Catalog No. PIPA596939

Description

Immunogen sequence: SSSKEENRII PGGIYDADLN DEWVQRALHF AISEYNKATE DEYYRRPLQV LRAREQTFGG VNYFFDVEVG RTICTKSQPN LDTCAFHEQP ELQKKQLCSF EIYEVPWEDR MSLVNSRCQE A; Positive Samples: BT-474.

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function.

Specifications

• Antigen: Cystatin S
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CST4
• Gene Alias: CST4; cystatin 4; cystatin S; cystatin-4; Cystatin-S; cystatin-SA-III; Salivary acidic protein 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1472
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.63 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P01036
• Gene Symbols: CST4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-141 of human CST4 (NP_0018901).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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