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  6. Epredia™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Epredia™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Catalog No. MS1248P Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Concentration
MS1248P 1 mL 200μg/mL
MS1248P0 100 μL 200μg/mL
MS1248P1 500 μL 200μg/mL
MS1248P1ABX 100 μL 1mg/mL
MS1248PABX 200 μL 1mg/mL
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Catalog No. MS1248P Supplier Epredia™ Supplier No. MS1248P

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Ensure accurate, reproducible results in immunofluorescence and immunoprecipitation experiments.

CFTR (cystic fibrosis transmembrane conductance regulator) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

Host Species: Mouse

Clone: L12B4

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: aa 386-412

Immunogen: Recombinant protein encoding NBF1 domain of human CFTR

Molecular Weight: 165-170 kDa

Positive Control: Pancreas

Cellular Localization: Membrane

Recommended for:

  • Western Blotting (Not verified)
  • Immunofluorescence
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3
Applications Immunofluorescence, Immunoprecipitation
Classification Monoclonal
Clone L12B4
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant protein encoding NBF1 domain of human CFTR
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Mouse, Rat
Form Concentrated
Isotype IgG1
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