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Cytochrome b245 alpha Antibody (CS9), Alexa Fluor™ 532, Novus Biologicals™
SDP

Catalog No. NP140974A32 Shop All R&D Systems Products
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NP140974A32 0.1 mL
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Catalog No. NP140974A32 Supplier Novus Biologicals Supplier No. NBP140974AF532
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Description

Mouse Monoclonal Antibody

Cytochrome b245 alpha Monoclonal specifically detects Cytochrome b245 alpha in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Frozen.

Specifications

Antigen Cytochrome b245 alpha
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone CS9
Conjugate Alexa Fluor 532
Dilution Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Frozen
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias cytochrome b light chain, Cytochrome b(558) alpha chain, cytochrome b(558) alpha-subunit, cytochrome b, alpha polypeptide, cytochrome b-245 light chain, cytochrome b-245, alpha polypeptide, Cytochrome b558 subunit alpha, flavocytochrome b-558 alpha polypeptide, Neutrophil cytochrome b 22 kDa polypeptide, p22 phagocyte B-cytochrome, p22phox, p22-phox, Superoxide-generating NADPH oxidase light chain subunit
Gene Symbols CYBA
Host Species Mouse
Immunogen Cytochrome B245 solubilised in octyl-beta-gluycopyranoside
Purification Method Protein G purified
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 1535.0
Test Specificity This antibody recognizes the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterized by severe recurrent infections.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1
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