Cytochrome b245 alpha Antibody (CS9), PE/Cy7, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP140974PECY7

Catalog No. N140974PEC7

Description

Cytochrome b245 alpha Monoclonal specifically detects Cytochrome b245 alpha in Human samples. It is validated for Flow Cytometry.

Specifications

• Antigen: Cytochrome b245 alpha
• Classification: Monoclonal
• Conjugate: PE-Cyanine7
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: CYBA
• Immunogen: Cytochrome B245 solubilised in octyl-beta-gluycopyranoside
• Quantity: 0.1 mL
• Gene ID (Entrez): 1535.0
• Target Species: Human
• Isotype: IgG1

• Applications: Flow Cytometry
• Clone: CS9
• Dilution: Flow Cytometry
• Gene Alias: cytochrome b light chain, Cytochrome b(558) alpha chain, cytochrome b(558) alpha-subunit, cytochrome b, alpha polypeptide, cytochrome b-245 light chain, cytochrome b-245, alpha polypeptide, Cytochrome b558 subunit alpha, flavocytochrome b-558 alpha polypeptide, Neutrophil cytochrome b 22 kDa polypeptide, p22 phagocyte B-cytochrome, p22phox, p22-phox, Superoxide-generating NADPH oxidase light chain subunit
• Host Species: Mouse
• Purification Method: Protein G purified
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterized by severe recurrent infections.
• Content And Storage: Store at 4°C in the dark. Do not freeze.