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Invitrogen™ Cytochrome C Monoclonal Antibody (6H2), FITC, eBioscience™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ 11660182

Encompass_Preferred

Catalog No. 50-997-3


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Description

Description

Description: The 6H2 antibody reacts with the native form of mouse, human, and rat cytochrome c. Applications Reported: The 6H2 antibody has been reported for use in intracellular flow cytometric analysis. Applications Tested: The 6H2 antibody has been tested by intracellular flow cytometric analysis. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.

Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Cytochrome C
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P62897, P62898, P99999
Cycs
Affinity chromatography
RUO
13063, 25309, 54205
4°C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry, Immunocytochemistry
6H2
FITC
Cycs
CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel\CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4
Mouse
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG1 κ
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