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Invitrogen™ Cytochrome C Polyclonal Antibody
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Catalog No. PIPA579119
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100 μg
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PIPA579119 100 μg
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Catalog No. PIPA579119 Supplier Invitrogen™ Supplier No. PA579119
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Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human HL-60 whole cell, human K562 whole cell, human U-937 whole cell, human U20S whole cell, human T-47D whole cell, human PC-3 whole cell, human CACO-2 whole cell, rat brain tissue, rat heart tissue, rat kidney tissue, rat C6 whole cell, mouse brain tissue, mouse heart tissue, mouse kidney tissue, mouse Neuro-2a whole cell. IHC: mouse brain tissue, mouse intestine tissue, rat brain tissue, rat intestine tissue.

Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytochrome C
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene Cycs
Gene Accession No. P62897, P62898, P99999
Gene Alias CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel\CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4
Gene Symbols Cycs
Host Species Rabbit
Immunogen E. coli-derived mouse Cytochrome C recombinant protein (Position: G2-E105).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13063, 25309, 54205
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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