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Cytochrome P450 2B6 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984659
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50-198-4659 100 μL
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Catalog No. 50-198-4659 Supplier Bioss Supplier No. BS2352R
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Description

Rabbit Polyclonal Antibody

This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Specifications

Antigen Cytochrome P450 2B6
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CYP2B6
Gene Accession No. P20813
Gene Alias 1,4-cineole 2-exo-monooxygenase; CPB6; CYP2B; CYP2B11; Cyp2b3; Cyp2b-3; CYP2B6; CYP2B7; CYP2B7P; CYPIIB11; CYPIIB3; CYPIIB6; Cytochrome P450 2B11; Cytochrome P450 2B3; Cytochrome P450 2B6; cytochrome P450 family 2 subfamily B member 6; Cytochrome P450 IIB1; Cytochrome P450 PBD-2; cytochrome P450, family 2, subfamily B, polypeptide 11; cytochrome P450, family 2, subfamily b, polypeptide 3; cytochrome P450, family 2, subfamily B, polypeptide 6; cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6; cytochrome P450IIB3; Cytochrome-P450-2B11; EFVM; IIB1; P450
Gene Symbols CYP2B6
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Cytochrome P450 2B6.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1555
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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