Invitrogen™ Cytochrome P450 Pan Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101312

Catalog No. PIPA5101312

Description

Antibody detects endogenous levels of total Cytochrome P450 2C8/9/18/19.

CYP2C9 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP2C9 localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin.

Specifications

• Antigen: Cytochrome P450 Pan
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYP2C9
• Gene Alias: (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; (S)-mephenytoin hydroxylase associated cytochrome P450; cholesterol 25-hydroxylase; CPC8; CPC9; CPCI; CPCJ; CYP2C; CYP2C10; CYP2C17; CYP2C18; CYP2C19; CYP2C8; CYP2C9; CYPIIC17; CYPIIC18; CYPIIC19; CYPIIC8; CYPIIC9; Cytochrome P450 2C18; cytochrome P450 2C19; Cytochrome P450 2C8; cytochrome P450 2C9; cytochrome P450 family 2 subfamily C member 18; cytochrome P450 family 2 subfamily C member 19; cytochrome P450 family 2 subfamily C member 8; cytochrome P450 family 2 subfamily C member 9; cytochrome P450 form 1; cytochrome P-450 II C; Cytochrome P450 IIC2; cytochrome P450 MP-12; Cytochrome P450 MP-20; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; cytochrome P-450 S-mephenytoin 4-hydroxylase; cytochrome P450, family 2, subfamily C, polypeptide 18; cytochrome P450, family 2, subfamily C, polypeptide 19; cytochrome P450, family 2, subfamily C, polypeptide 8; cytochrome P450, family 2, subfamily C, polypeptide 9; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8; cytochrome P450-11A; Cytochrome P450-254C; cytochrome P450-6B/29C; cytochrome P-450MP; Fenbendazole monooxygenase (4'-hydroxylating); flavoprotein-linked monooxygenase; mephenytoin 4'-hydroxylase; mephenytoin 4-hydroxylase; microsomal monooxygenase; MP-12/MP-20; P450 form 1; P450-6B/29C; P450C2C; P450IIC17; P450IIC19; P450IIC9; s-mephenytoin 4-hydroxylase; unspecific monooxygenase; xenobiotic monooxygenase
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13106, 1557, 1558, 1559, 1562, 1571
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P05181, P10632, P11712, P33260, P33261, Q05421
• Gene Symbols: CYP2C18, CYP2C19, CYP2C8, CYP2C9, CYP2E1
• Immunogen: A synthesized peptide derived from human CYP2C18(Accession P33260), corresponding to amino acid residues N116-P166.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov