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Invitrogen™ Cytochrome P450 Reductase Polyclonal Antibody
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Catalog No. PIPA527328
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100 μL
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PIPA527328 100 μL
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Catalog No. PIPA527328 Supplier Invitrogen™ Supplier No. PA527328
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, HepG2, mouse liver. Predicted reactivity: Mouse (90%), Rat (90%), Dog (93%), Pig (87%), Rabbit (88%), Rhesus Monkey (98%), Bovine (93%), Guinea pig (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytochrome P450 Reductase
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.73 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene POR
Gene Accession No. P16435, P37040
Gene Alias 4933424M13Rik; CCR; CPR; CY DKFZp686G04235; CYPOR; cytochrome p450 oxidoreductase; cytochrome P450 reductase; DKFZp686G04235; FLJ26468; I79_007261; LOC101115252; NADPH Cytochrome; NADPH-cytochrome P450 oxidoreductase; NADPH-cytochrome P-450 oxidoreductase; NADPH-cytochrome P450 reductase; NADPH--cytochrome P450 reductase; NADPH-cytochrome P-450 reductase; NADPH-dependent cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450 Reductase; P450R; Por; unnamed protein product
Gene Symbols POR
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human POR. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18984, 5447
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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