Cytohesin 1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 142171AP150UL

Catalog No. 50-172-9290

Description

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2.

Specifications

• Antigen: Cytohesin 1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYTH1
• Gene Alias: B2 1, CYTH1, cytohesin 1, D17S811E, PSCD1, SEC7, SEC7 homolog B2 1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116691, 19157, 9267
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.23 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P97694, Q15438, Q9QX11
• Gene Symbols: Cyth1
• Immunogen: Cytohesin 1 Fusion Protein Ag5455
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG