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Invitrogen™ Cytohesin 2 Monoclonal Antibody (CYT2-21)
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Catalog No. PIMA125510
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50 μL
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Catalog No. Quantity
PIMA125510 50 μL
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Catalog No. PIMA125510 Supplier Invitrogen™ Supplier No. MA125510
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Description

Mouse Monoclonal Antibody

Recommended positive controls: rat brain. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytohesin 2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone CYT2-21
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene CYTH2
Gene Accession No. P63035, Q99418
Gene Alias ARF exchange factor; ARF nucleotide binding site opener; ARF nucleotide-binding site opener; ARNO; CLM2; CTC-273B12.8; CTS18; CTS18.1; Cyth2; cytohesin 2; cytohesin-2; mSec7-2; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2); pleckstrin homology, Sec7 and coiled-coil domains 2; pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2); Protein ARNO; PSCD2; PSCD2L; Sec7; SEC7 homolog B; Sec7b; SEC7L; Sec7p-L; Sec7p-like
Gene Symbols CYTH2
Host Species Mouse
Immunogen Recombinant, human ARNO (ARFnucleotide-binding-site opener).
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116692, 9266
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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