Invitrogen™ Cytohesin 2 Monoclonal Antibody (CYT2-21)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA125510

Catalog No. PIMA125510

Description

Recommended positive controls: rat brain. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Cytohesin 2
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 15 mM sodium azide; pH 7.4
• Gene Accession No.: P63035, Q99418
• Gene Symbols: CYTH2
• Immunogen: Recombinant, full length human protein.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: CYT2-21
• Conjugate: Unconjugated
• Gene: CYTH2
• Gene Alias: ARF exchange factor; ARF nucleotide binding site opener; ARF nucleotide-binding site opener; ARNO; CLM2; CTC-273B12.8; CTS18; CTS18.1; Cyth2; cytohesin 2; cytohesin-2; mSec7-2; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2); pleckstrin homology, Sec7 and coiled-coil domains 2; pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2); Protein ARNO; PSCD2; PSCD2L; Sec7; SEC7 homolog B; Sec7b; SEC7L; Sec7p-L; Sec7p-like
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 116692, 9266
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid