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  6. Cytohesin 3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech 

Cytohesin 3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501731114 Shop All Proteintech Group Inc Products
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50-173-1114 150 μL
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Catalog No. 50-173-1114 Supplier Proteintech Group Inc Supplier No. 166871AP150UL
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Description

Rabbit Polyclonal Antibody

GRP1 (general receptor for phosphoinositides-1) contains a Pleckstrin homology (PH) domain as well as a Sec7 domain. The PH domain has high binding affinity for phosphatidylinositol 3,4,5-trisphosphate Ptdlns(3,4,5)P3), while the Sec7 homology domain is responsible for catalyzing guanine nucleotide exchange of ADP-ribosylation factor (ARF) proteins. GRP1 co-localizes with ARF6 and catalyzes GTP/GDP exchange on ARF6. It is known to interact with Ptdlns(3,4,5)P3 localized to the plasma membrane in vitro and may also be a Ptdlns(3,4,5)P3 receptor. Additionally, GRP1 may regulate protein sorting and membrane trafficking through interaction with the guanosine triphosphate ARF, and may control cell adhesion through interaction with integrins.

Specifications

Antigen Cytohesin 3
Applications Western Blot
Classification Polyclonal
Concentration 0.48 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CYTH3
Gene Accession No. O08967, O43739, P97696
Gene Alias ARNO3, CYTH3, cytohesin 3, GRP1, Protein ARNO3, PSCD3
Gene Symbols Cyth3
Host Species Rabbit
Immunogen Cytohesin 3 Fusion Protein Ag10025
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116693, 19159, 9265
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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