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Cytohesin 3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 166871AP

Catalog No. 50-173-1114


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Description

Description

GRP1 (general receptor for phosphoinositides-1) contains a Pleckstrin homology (PH) domain as well as a Sec7 domain. The PH domain has high binding affinity for phosphatidylinositol 3,4,5-trisphosphate Ptdlns(3,4,5)P3), while the Sec7 homology domain is responsible for catalyzing guanine nucleotide exchange of ADP-ribosylation factor (ARF) proteins. GRP1 co-localizes with ARF6 and catalyzes GTP/GDP exchange on ARF6. It is known to interact with Ptdlns(3,4,5)P3 localized to the plasma membrane in vitro and may also be a Ptdlns(3,4,5)P3 receptor. Additionally, GRP1 may regulate protein sorting and membrane trafficking through interaction with the guanosine triphosphate ARF, and may control cell adhesion through interaction with integrins.
Specifications

Specifications

Cytohesin 3
0.48 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O08967, O43739, P97696
ARNO3, CYTH3, cytohesin 3, GRP1, Protein ARNO3, PSCD3
Rabbit
IgG
150 μL
-20°C
Primary
116693, 19159, 9265
Western Blot
Unconjugated
CYTH3
Liquid
Cyth3
Cytohesin 3 Fusion Protein Ag10025
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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