Invitrogen™ Cytokeratin 1 Polyclonal Antibody

Catalog No.	Quantity
PIPA5113746	100 μL

Catalog No. PIPA5113746 Supplier Invitrogen™ Supplier No. PA5113746

Description

Rabbit Polyclonal Antibody

Immunogen sequence: GSYGSGSSSG GYRGGSGGGG GGSSGGRGSG GGSSGGSIGG RGSSSGGVKS For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Dog: 86%; Human: 100%; Rabbit: 93%; Rat: 93%.

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Specifications

• Antigen: Cytokeratin 1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene: KRT1
• Gene Accession No.: P04264
• Gene Alias: 67 kDa cytokeratin; CK1; CK-1; cytokeratin 1; cytokeratin-1; EHK; EHK1; epidermolytic hyperkeratosis 1; epithelial keratin 1; Epithelial keratin-1; EPPK; Hair alpha protein; K1; Kb1; KER1; keratin 1; keratin 1 (epidermolytic hyperkeratosis); keratin 1, type II; keratin 86; keratin complex 2, basic, gene 1; keratin, type II cytoskeletal 1; Keratin-1; KRT1; krt1 {ECO:0000250; KRT1A; Krt-2.1; Krt2-1; Krt86; KRTA; NEPPK; type II keratin Kb1; type-II keratin Kb1; UniProtKB:P04264}
• Gene Symbols: KRT1
• Host Species: Rabbit
• Immunogen: Synthetic peptide directed towards the middle region of human KRT1.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3848
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG