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Invitrogen™ Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody (10W8J6)
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Catalog No. PIMA538216
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PIMA538216 100 μL
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Catalog No. PIMA538216 Supplier Invitrogen™ Supplier No. MA538216
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: Mouse brain, Rat brain, A375 Immunogen sequence: GGGGRGSYGS GGSSYGSGGG SYGSGGGGGG HGSYGSGSSS GGYRGGSGGG GGGSSGGRGS GGGSSGGSIG GRGSSSGGVK SSGGSSSVKF VSTTYSGVTR.

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 10W8J6
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KRT1
Gene Accession No. P04104, P04264, Q6IMF3
Gene Alias 67 kDa cytokeratin; CK1; CK-1; cytokeratin 1; cytokeratin-1; EHK; EHK1; epidermolytic hyperkeratosis 1; epithelial keratin 1; Epithelial keratin-1; EPPK; Hair alpha protein; K1; Kb1; KER1; keratin 1; keratin 1 (epidermolytic hyperkeratosis); keratin 1, type II; keratin 86; keratin complex 2, basic, gene 1; keratin, type II cytoskeletal 1; Keratin-1; KRT1; krt1 {ECO:0000250; KRT1A; Krt-2.1; Krt2-1; Krt86; KRTA; NEPPK; type II keratin Kb1; type-II keratin Kb1; UniProtKB:P04264}
Gene Symbols KRT1
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16678, 300250, 3848
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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