Invitrogen™ Cytokeratin 10 Monoclonal Antibody (AE20)

Catalog No.	Quantity
01-674-885	100 μL

Catalog No. 01-674-885 Supplier Invitrogen™ Supplier No. MA15766

Description

Mouse Monoclonal Antibody

MA1-5766 detects Cytokeratin K10-1, AE20 in human samples. MA1-5766 has been successfully used in Western blot and immunohistochemistry procedures. The MA1-5766 immunogen is human epidermal keratins.

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e., skin) and non-keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8. 5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.

Specifications

• Antigen: Cytokeratin 10
• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: AE20
• Concentration: 1.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide
• Gene: KRT10
• Gene Accession No.: P13645
• Gene Alias: 56 kDa cytokeratin; BCIE; BIE; CK10; CK-10; CK-17; cytokeratin 10; cytokeratin-10; cytokeratin-17; D130054E02Rik; EHK; epidermal keratin 10; epithelial keratin 10; intermediate filament protein; K10; K1C1; Ka10; Ker10; keratin 10; keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris); keratin 10, type I; keratin complex 1, acidic, gene 10; keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 59 kDa; keratin-10; keratin-17; KPP; Krt-1.10; KRT10; krt10 {ECO:0000250; Krt1-10; suprabasal cytokeratin 10; type I keratin KA10; UniProtKB:P13645}
• Gene Symbols: KRT10
• Host Species: Mouse
• Immunogen: Human epidermal keratins from P3 x 63 Ag8 cells.
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3858
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1