Invitrogen™ Cytokeratin 13 Monoclonal Antibody (2D7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA135542

Catalog No. 01-671-380

Description

The antibody does not stain non-cornifying squamous epithelium and transitional epithelium of the bladder. In immunoblotting experiments the antibody recognizes only keratin no. 13 (54 kDa).

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ~40 kDa and ~68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Specifications

• Antigen: Cytokeratin 13
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: tissue culture supernatant with 0.01M sodium azide
• Gene Accession No.: P13646
• Gene Symbols: KRT13
• Immunogen: Cytokeratin purified from human esophagus.
• Regulatory Status: RUO
• Gene ID (Entrez): 3860
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Western Blot
• Clone: 2D7
• Conjugate: Unconjugated
• Gene: KRT13
• Gene Alias: 47 kDa cytokeratin; CK13; CK-13; cytokeratin 13; cytokeratin-13; K13; K-13; Ka13; keratin 13; keratin 13, type I; keratin complex 1, acidic, gene 13; keratin, type I cytoskeletal 13; Keratin-13; Krt-1.13; Krt1-13; KRT13; krt13 {ECO:0000250; MGC161462; MGC3781; Type I keratin Ka13; UniProtKB:P13646}; WSN2
• Host Species: Mouse
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov