Invitrogen™ Cytokeratin 13 Monoclonal Antibody (AE8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA15764

Catalog No. 01-674-883

Description

MA1-5764 detects Cytokeratin K13, AE8 in human samples. MA1-5764 has been successfully used in Western blot and immunohistochemistry procedures. The MA1-5764 immunogen is Rabbit esophageal keratins.

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ~40 kDa and ~68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Specifications

• Antigen: Cytokeratin 13
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: P08730, P13646
• Gene Symbols: KRT13
• Immunogen: Rabbit esophageal keratins from P3 x 63 Ag8 cells.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rabbit
• Product Type: Antibody
• Isotype: Ig

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: AE8
• Conjugate: Unconjugated
• Gene: KRT13
• Gene Alias: 47 kDa cytokeratin; CK13; CK-13; cytokeratin 13; cytokeratin-13; K13; K-13; Ka13; keratin 13; keratin 13, type I; keratin complex 1, acidic, gene 13; keratin, type I cytoskeletal 13; Keratin-13; Krt-1.13; Krt1-13; KRT13; krt13 {ECO:0000250; MGC161462; MGC3781; Type I keratin Ka13; UniProtKB:P13646}; WSN2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100344183, 16663, 3860
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid