Cytokeratin 13 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA596764

Catalog No. PIPA596764

Description

Immunogen sequence: DLTRVLAEMR EQYEAMAERN RRDAEEWFHA KSAELNKEVS TNTAMIQTSK TEITELRRTL QGLEIELQSQ LSMKAGLENT VAETECRYAL QLQQIQGLIS SIEAQLSELR SEMECQNQEY KMLLDIKTRL EQEIATYRSL LEGQDAKMIG FPSSAGSVSP RSTSVTTTSS ASVTTTSNAS GRRTSDVRRP; Positive Samples: MCF7, Mouse intestine, Rat thymus

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ∽40 kDa and ∽68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Specifications

• Antigen: Cytokeratin 13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KRT13
• Gene Alias: 47 kDa cytokeratin, CK13, CK-13, cytokeratin 13, cytokeratin-13, K13, K-13, Ka13, keratin 13, keratin 13, type I, keratin complex 1, acidic, gene 13, keratin, type I cytoskeletal 13, Keratin-13, Krt-1.13, Krt1-13, KRT13, krt13 {ECO:0000250, MGC161462, MGC3781, Type I keratin Ka13, UniProtKB:P13646}, WSN2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16663, 287699, 3860
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
• Gene Accession No.: P08730, P13646, Q6IFV4
• Gene Symbols: KRT13
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 269-458 of human Cytokeratin 13 (Cytokeratin 13 (KRT13)) (NP_7056942)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG