Invitrogen™ Cytokeratin 13 Recombinant Rabbit Monoclonal Antibody (SN71-09)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA532305

Catalog No. PIMA532305

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ~40 kDa and ~68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Specifications

• Antigen: Cytokeratin 13
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P08730, P13646
• Gene Symbols: KRT13
• Immunogen: Synthetic peptide within Human Cytokeratin 13 aa 111-160.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Zebrafish
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Clone: SN71-09
• Conjugate: Unconjugated
• Gene: KRT13
• Gene Alias: 47 kDa cytokeratin; CK13; CK-13; cytokeratin 13; cytokeratin-13; K13; K-13; Ka13; keratin 13; keratin 13, type I; keratin complex 1, acidic, gene 13; keratin, type I cytoskeletal 13; Keratin-13; Krt-1.13; Krt1-13; KRT13; krt13 {ECO:0000250; MGC161462; MGC3781; Type I keratin Ka13; UniProtKB:P13646}; WSN2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 16663, 3860
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid