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Invitrogen™ Cytokeratin 14 Polyclonal Antibody
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Catalog No. PIPA528002
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100 μL
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PIPA528002 100 μL
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Catalog No. PIPA528002 Supplier Invitrogen™ Supplier No. PA528002
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, rat olfactory epithelium. Predicted reactivity: Mouse (95%), Rat (94%), Dog (96%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 14
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.51 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene KRT14
Gene Accession No. P02533, Q6IFV1
Gene Alias AI626930; CK14; CK-14; cytokeratin 14; cytokeratin-14; EBS3; EBS4; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; Ka14; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin complex 1, acidic, gene 14; keratin, type I cytoskeletal 14; keratin, type I cytoskeletal 17; keratin-14; Koebner; Krt-1.14; Krt1-14; KRT14; LOC100737113; NFJ; Type I keratin Ka14
Gene Symbols KRT14
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Cytokeratin 14. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 287701, 3861
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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