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Invitrogen™ Cytokeratin 14 Polyclonal Antibody
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Catalog No. PIPA516722
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500 μL
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PIPA516722 500 μL
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Catalog No. PIPA516722 Supplier Invitrogen™ Supplier No. PA516722
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Description

Rabbit Polyclonal Antibody

PA5-16722 targets Cytokeratin 14 in immunohistochemistry (paraffin and Western blot applications and shows reactivity with Human samples. The PA5-16722 immunogen is a synthetic peptide derived from C-terminal of human Keratin 14.

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 14
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.235 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene KRT14
Gene Accession No. P02533, Q61781
Gene Alias AI626930; CK14; CK-14; cytokeratin 14; cytokeratin-14; EBS3; EBS4; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; Ka14; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin complex 1, acidic, gene 14; keratin, type I cytoskeletal 14; keratin, type I cytoskeletal 17; keratin-14; Koebner; Krt-1.14; Krt1-14; KRT14; LOC100737113; NFJ; Type I keratin Ka14
Gene Symbols KRT14
Host Species Rabbit
Immunogen A synthetic peptide derived from C-terminal of human Keratin 14.
Purification Method Antigen affinity chromatography
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16664, 3861
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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