Invitrogen™ Cytokeratin 16 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527282

Catalog No. PIPA527282

Description

Recommended positive controls: HeLa. Predicted reactivity: Chimpanzee (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.

Specifications

• Antigen: Cytokeratin 16
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KRT16
• Gene Alias: AI324768; CK16; CK-16; cytokeratin 16; cytokeratin-16; FNEPPK; focal non-epidermolytic palmoplantar keratoderma; K16; K1CP; Ka16; keratin 16; keratin 16, type I; keratin complex 1, acidic, gene 16; keratin intermediate filament 16a; keratin intermediate filament 16b; keratin, type I cytoskeletal 16; Keratin-16; Krt1-16; Krt16; KRT16A; NEPPK; PC1; type I keratin KA16
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3868
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.77 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P08779
• Gene Symbols: KRT16
• Immunogen: Recombinant fragment corresponding to a region within amino acids 344 and 473 of Human Cytokeratin 16.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG