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Invitrogen™ Cytokeratin 17 Monoclonal Antibody (3B12)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA515534
Description
MA5-15534 targets CK17 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15534 immunogen is purified recombinant fragment of CK17 expressed in E. Coli. MA5-15534 detects CK17 which has a predicted molecular weight of approximately 49kDa.
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
Specifications
Cytokeratin 17 | |
Monoclonal | |
Conc. Not Determined | |
Ascites with 0.03% sodium azide | |
Q04695 | |
KRT17 | |
Purified recombinant fragment of CK17 expressed in E. Coli. | |
RUO | |
3872 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
ELISA, Immunohistochemistry (Paraffin), Western Blot | |
3B12 | |
Unconjugated | |
KRT17 | |
39.1; CK17; CK-17; cytokeratin-17; hard keratin; K17; Ka17; keratin 17; keratin 17, type I; keratin complex 1, acidic, gene 17; keratin, type I cytoskeletal 17; Keratin-17; Krt1-17; Krt17; krt17 {ECO:0000250; PC; PC2; PCHC1; Type I keratin Ka17; UniProtKB:Q04695} | |
Mouse | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG2b |
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