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Invitrogen™ Cytokeratin 17 Monoclonal Antibody (3B12)
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Catalog No. PIMA515534
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100 μL
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PIMA515534 100 μL
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Catalog No. PIMA515534 Supplier Invitrogen™ Supplier No. MA515534
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Description

Mouse Monoclonal Antibody

MA5-15534 targets CK17 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15534 immunogen is purified recombinant fragment of CK17 expressed in E. Coli. MA5-15534 detects CK17 which has a predicted molecular weight of approximately 49kDa.

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 17
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 3B12
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene KRT17
Gene Accession No. Q04695
Gene Alias 39.1; CK17; CK-17; cytokeratin-17; hard keratin; K17; Ka17; keratin 17; keratin 17, type I; keratin complex 1, acidic, gene 17; keratin, type I cytoskeletal 17; Keratin-17; Krt1-17; Krt17; krt17 {ECO:0000250; PC; PC2; PCHC1; Type I keratin Ka17; UniProtKB:Q04695}
Gene Symbols KRT17
Host Species Mouse
Immunogen Purified recombinant fragment of CK17 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3872
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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