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Cytokeratin 17 Monoclonal Antibody (E3), Invitrogen™

Catalog No. PIMA513539
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500 μL
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PIMA513539 500 μL
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Catalog No. PIMA513539 Supplier Thermo Scientific Supplier No. MA513539

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Mouse Monoclonal Antibody

MA5-13539 targets Cytokeratin 17 in IF and IHC (P) applications and shows reactivity with Human and Rat samples. The MA5-13539 immunogen is keratin preparation from rat enterocytes.

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 17
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone E3
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation tissue culture supernatant with 0.09% sodium azide
Gene KRT17
Gene Accession No. Q04695, Q6IFU8
Gene Alias 39.1; CK17; CK-17; cytokeratin-17; hard keratin; K17; Ka17; keratin 17; keratin 17, type I; keratin complex 1, acidic, gene 17; keratin, type I cytoskeletal 17; Keratin-17; Krt1-17; Krt17; krt17 {ECO:0000250; PC; PC2; PCHC1; Type I keratin Ka17; UniProtKB:Q04695}
Gene Symbols KRT17
Host Species Mouse
Immunogen Keratin preparation from rat enterocytes
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 287702, 3872
Target Species Human, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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