Invitrogen™ Cytokeratin 17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110615

Catalog No. PIPA5110615

Description

Immunogen sequence: TMQALEIELQ SQLSMKASLE GNLAETENRY CVQLSQIQGL IGSVEEQLAQ LRCEMEQQNQ EYKILLDVKT RLEQEIATYR RLLEGEDAHL TQYKKEPVTT RQVRTIVEEV QDGKVISSRE QVHQT.

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Specifications

• Antigen: Cytokeratin 17
• Classification: Polyclonal
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q04695
• Gene Symbols: KRT17
• Immunogen: Recombinant Protein corresonding to Human Cytokeratin 17. Recombinant protein control fragment (Product #RP-96646).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: KRT17
• Gene Alias: 39.1; CK17; CK-17; cytokeratin-17; hard keratin; K17; Ka17; keratin 17; keratin 17, type I; keratin complex 1, acidic, gene 17; keratin, type I cytoskeletal 17; Keratin-17; Krt1-17; Krt17; krt17 {ECO:0000250; PC; PC2; PCHC1; Type I keratin Ka17; UniProtKB:Q04695}
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3872
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov