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Invitrogen™ Cytokeratin 19 Polyclonal Antibody
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Catalog No. PIPA587389
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100 μL
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PIPA587389 100 μL
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Catalog No. PIPA587389 Supplier Invitrogen™ Supplier No. PA587389
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse stomach Immunogen sequence: ELAYLKKNHE EEISTLRGQV GGQVSVEVDS APGTDLAKIL SDMRSQYEVM AEQNRKDAEA WFTSRTEELN REVAGHTEQL QMSRSEVTDL RRTLQGLEIE LQSQLSMKAA LEDTLAETEA RFGAQLAHIQ A.

Cytokeratin 19 is part of a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight from 40-68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. For example, cytokeratin 19 is not expressed in hepatocytes, therefore, it is useful in the identification of liver metastasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 19
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KRT19
Gene Accession No. P08727, P19001, Q63279
Gene Alias 40-kDa keratin intermediate filament; AI663979; C K1CS; CK 19; CK19; CK-19; cytokeratin 19; cytokeratin-19; EndoC; K19; K1CS; Ka19; keratin 19; keratin 19, type I; keratin complex 1, acidic, gene 19; keratin, type I cytoskeletal 19; keratin, type I, 40-kd; keratin-19; Krt-1.19; Krt1-19; Krt19; LOC100344434; MGC15366; Type I keratin Ka19
Gene Symbols KRT19
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 210-340 of human Cytokeratin 19 (KRT19) (NP_0022672).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16669, 360626, 3880
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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