Invitrogen™ Cytokeratin 4 Monoclonal Antibody (6B10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA106313

Catalog No. MA106313

Description

MA1-06313 detects cytokeratin 4 in human, canine, zebrafish, and feline samples. MA1-06313 has sucessfully been used in Western blotting, flow cytometry, immunocytochemistry, and immunoprecipitation. The MA1-06313 immunogen is a cytokeratin preparation extracted from human esophagus.

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9-7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Specifications

• Antigen: Cytokeratin 4
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: P19013
• Gene Symbols: KRT4
• Immunogen: Cytokeratin preparation extracted from human esophagus.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Canine, Feline, Zebrafish
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 6B10
• Conjugate: Unconjugated
• Gene: KRT4
• Gene Alias: 57kd keratin; 57kDa keratin; AW108092; cb59; CK4; CK-4; CYK4; cytokeratin; cytokeratin 4; cytokeratin-4; Cytoskeletal 57 kDa keratin; etID20321.6; intermediate filament protein; K4; Kb4; keratin 4; keratin 4, type II; keratin 8; keratin complex 2, basic, gene 4; keratin, type II cytoskeletal 4; Keratin-4; Krt-2.4; Krt2-4; Krt4; krt4 {ECO:0000250; krt4 protein; krt8; type II basic cytokeratin; type II keratin Kb4; type-II keratin Kb4; UniProtKB:P19013}; WSN1; wu:fa91a11; wu:fd19e09; wu:fl23c09; zf-K8
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 100682832, 101080551, 3851, 794486
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov