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Invitrogen™ Cytokeratin 4 Recombinant Rabbit Monoclonal Antibody (6H9R6)
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Catalog No. PIMA537810
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PIMA537810 100 μL
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Catalog No. PIMA537810 Supplier Invitrogen™ Supplier No. MA537810
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: A-549, A-431, Mouse stomach Immunogen sequence: MIARQQCVRG GPRGFSCGSA IVGGGKRGAF SSVSMSGGAG RCSSGGFGSR SLYNLRGNKS ISMSVAGSRQ GACFGGAGGF GTGGFGGGFG GSFSGKGGPG.

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9-7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 4
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 6H9R6
Concentration 0.42 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KRT4
Gene Accession No. P07744, P19013, Q6IG00
Gene Alias 57kd keratin; 57kDa keratin; AW108092; cb59; CK4; CK-4; CYK4; cytokeratin; cytokeratin 4; cytokeratin-4; Cytoskeletal 57 kDa keratin; etID20321.6; intermediate filament protein; K4; Kb4; keratin 4; keratin 4, type II; keratin 8; keratin complex 2, basic, gene 4; keratin, type II cytoskeletal 4; Keratin-4; Krt-2.4; Krt2-4; Krt4; krt4 {ECO:0000250; krt4 protein; krt8; type II basic cytokeratin; type II keratin Kb4; type-II keratin Kb4; UniProtKB:P19013}; WSN1; wu:fa91a11; wu:fd19e09; wu:fl23c09; zf-K8
Gene Symbols KRT4
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cytokeratin 4 (KRT4) (P19013).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16682, 315323, 3851
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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