Invitrogen™ Cytokeratin 5/14 Monoclonal Antibody (LH8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA190930

Catalog No. PIMA190930

Description

MA1-90930 detects Cytokeratin 5 + 14 from human samples.

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Specifications

• Antigen: Cytokeratin 5/14
• Classification: Monoclonal
• Concentration: 0.8 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P02533, P13647
• Gene Symbols: KRT14, KRT5
• Immunogen: The 50,000 Mr band (including K14 )cut from an SDS-polyacrylamide gel and Triton X-100 extracted cytoskeleton pellet from cultured human foreskin keratinocytes.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgM

• Applications: Immunohistochemistry
• Clone: LH8
• Conjugate: Unconjugated
• Gene: KRT5
• Gene Alias: 58 kda cytokeratin; CK14; CK-14; CK5; CK-5; cytokeratin 14; cytokeratin-14; Cytokeratin-5; DDD; DDD1; EBS2; EBS3; EBS4; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K14; K5; keratin 14; keratin 14, type I; keratin 5; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin, type I cytoskeletal 14; Keratin, type II cytoskeletal 5; keratin-14; Keratin-5; KRT14; KRT5; KRT5A; NFJ; Type-II keratin Kb5
• Host Species: Mouse
• Purification Method: IgG fraction
• Regulatory Status: RUO
• Gene ID (Entrez): 3852, 3861
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid