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Invitrogen™ Cytokeratin 5/14 Monoclonal Antibody (LH8)
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Catalog No. PIMA190930
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100 μg
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Catalog No. Quantity
PIMA190930 100 μg
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Catalog No. PIMA190930 Supplier Invitrogen™ Supplier No. MA190930
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Description

Mouse Monoclonal Antibody

MA1-90930 detects Cytokeratin 5 + 14 from human samples.

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 5/14
Applications Immunohistochemistry
Classification Monoclonal
Clone LH8
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene KRT5
Gene Accession No. P02533, P13647
Gene Alias 58 kda cytokeratin; CK14; CK-14; CK5; CK-5; cytokeratin 14; cytokeratin-14; Cytokeratin-5; DDD; DDD1; EBS2; EBS3; EBS4; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K14; K5; keratin 14; keratin 14, type I; keratin 5; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin, type I cytoskeletal 14; Keratin, type II cytoskeletal 5; keratin-14; Keratin-5; KRT14; KRT5; KRT5A; NFJ; Type-II keratin Kb5
Gene Symbols KRT14, KRT5
Host Species Mouse
Immunogen The 50,000 Mr band (including K14 )cut from an SDS-polyacrylamide gel and Triton X-100 extracted cytoskeleton pellet from cultured human foreskin keratinocytes.
Purification Method IgG fraction
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3852, 3861
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgM
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