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Invitrogen™ Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody (3F7A1)
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Catalog No. PIMA538024
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PIMA538024 100 μL
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Catalog No. PIMA538024 Supplier Invitrogen™ Supplier No. MA538024
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: 5637, A-431 Immunogen sequence: YRKLLEGEEC RLNGEGVGQV NVSVVQSTIS SGYGGASGVG SGLGLGGGSS YSYGSGLGIG GGFSSSSGRA IGGGLSSVGG GSSTIKYTTT SSSSRKSYKH.

Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 6
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 3F7A1
Concentration 0.17 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KRT6A
Gene Accession No. P02538, P04259, P48668
Gene Alias 2310016L08Rik; 60-kDa keratin; BB144589; CK6A; CK-6A; CK6B; CK-6B; CK6C; CK-6C; CK6D; CK-6D; CK-6E; cytokeratin 6A; cytokeratin 6B; cytokeratin 6C; cytokeratin 6D; cytokeratin-6A; Cytokeratin-6B; cytokeratin-6C; Cytokeratin-6D; Cytokeratin-6E; Hom s 5; K6A; K6a keratin; K6B; K6C; K6D; K6E; kamp-keratin derived antimicrobial peptide; KDAMP; Ker2; keratin 6A; keratin 6A, , type II; keratin 6A, type II; keratin 6B; keratin 6B, type II; keratin 6C; keratin 6C, type II; keratin 6E; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6b; keratin complex 2, basic, gene 6c; keratin complex 2, gene 6a; keratin K6; keratin K6h; keratin, epidermal type II, K6A; keratin, epidermal, type II, K6B; keratin, type II cytoskeletal 6A; Keratin, type II cytoskeletal 6B; keratin, type II cytoskeletal 6C; keratin-6A; Keratin-6-alpha; Keratin-6B; keratin-6-beta; keratin-6C; keratin-like 1 (a type II keratin sequence); Krt2-6; Krt2-6a; Krt2-6b; Krt2-6c; Krt6; Krt6a; Krt6b; KRT6C; KRT6D; KRT6E; KRTL1; LOC683313; mK6[a]; mK6[b]; MK6a; mK6-alpha; mK6-beta; PC2; PC3; PC4; PPKNEFD; similar to keratin complex 2, basic, gene 6a; type-II keratin Kb10; Type-II keratin Kb12; type-II keratin Kb6
Gene Symbols KRT6A, KRT6B, KRT6C
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 465-564 of human Cytokeratin 6 (KRT6) (P48668).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 286887, 3853, 3854
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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