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Cytokeratin 6A Monoclonal Antibody (LHK6B), Invitrogen™

Catalog No. PIMA514127
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PIMA514127 500 μL
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Catalog No. PIMA514127 Supplier Thermo Scientific Supplier No. MA514127
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Description

Mouse Monoclonal Antibody

MA5-14127 targets Cytokeratin 6 in FN applications and shows reactivity with Human and mouse samples. The MA5-14127 immunogen is a synthetic peptide (GSSTIKYTTTS) from the C-terminus of human keratin 6.

Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 6A
Applications Immunohistochemistry
Classification Monoclonal
Clone LHK6B
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene KRT6A
Gene Accession No. P02538, P50446
Gene Alias 2310016L08Rik; 60-kDa keratin; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; Hom s 5; K6A; K6a keratin; K6C; K6D; kamp-keratin derived antimicrobial peptide; KDAMP; Ker2; keratin 6A; keratin 6A, , type II; keratin 6A, type II; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, gene 6a; keratin K6; keratin K6h; keratin, epidermal type II, K6A; keratin, type II cytoskeletal 6A; keratin, type II cytoskeletal 6C; Keratin-6A; keratin-6-alpha; keratin-6C; Krt2-6; Krt2-6a; Krt2-6c; Krt6; KRT6A; KRT6C; KRT6D; LOC683313; mK6[a]; MK6a; mK6-alpha; PC3; similar to keratin complex 2, basic, gene 6a; type-II keratin Kb12; type-II keratin Kb6
Gene Symbols KRT6A
Host Species Mouse
Immunogen A synthetic peptide (GSSTIKYTTTS) from the C-terminus of human keratin 6
Purification Method Protein A
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16687, 3853
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG2a
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