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Invitrogen™ Cytokeratin 7/17 Monoclonal Antibody (C-46)
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Catalog No. 01675018
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100 μg
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Catalog No. Quantity
01-675-018 100 μg
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Catalog No. 01-675-018 Supplier Invitrogen™ Supplier No. MA119045
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Description

Mouse Monoclonal Antibody

This antibody reacts with cytokeratin peptides 7 and 17 (54 and 46 kDa). Cytokeratins are members of intermediate filaments subfamily of intracellular proteins represented in epithelial tissues. This antibody will not cross-react with mouse, rat or rabbit.

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ~40 kDa and ~68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
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Specifications

Antigen Cytokeratin 7/17
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone C-46
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene KRT7
Gene Accession No. A1L595, P08729, Q04695, Q29S21
Gene Alias 39.1; CK-17; CK7; CK-7; cytokeratin 7; cytokeratin-17; Cytokeratin-7; K17; K2C7; K7; keratin 14; keratin 17; keratin 17, type I; keratin 7; keratin 7, type II; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; keratin, type I cytoskeletal 17; Keratin, type II cytoskeletal 7; keratin-17; Keratin-7; keratin-associated protein 7-1; KRT14; KRT17; KRT7; LOC100626483; LOC100737113; PC; PC2; PCHC1; sarcolectin; SCL; similar to keratin 7; type II mesothelial keratin K7; type-II keratin Kb7
Gene Symbols KRT17, KRT7, LOC100626483
Host Species Mouse
Immunogen Cytoskeleton preparation of HeLa human cervix carcinoma cell line.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100626483, 100626722, 281889, 3855, 3872, 535697
Target Species Human, Bovine, Pig
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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