Invitrogen™ Cytokeratin 8 Monoclonal Antibody (8A5D12)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515460

Catalog No. PIMA515460

Description

MA5-15460 targets Cytokeratin 8 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-15460 immunogen is purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. Coli. MA5-15460 detects Cytokeratin 8 which has a predicted molecular weight of approximately 54kDa.

Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Specifications

• Antigen: Cytokeratin 8
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: P05787
• Gene Symbols: KRT8
• Immunogen: Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 3856
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 8A5D12
• Conjugate: Unconjugated
• Gene: KRT8
• Gene Alias: AA960620; AL022697; AU019895; CARD2; cb186; CK8; CK-8; CYK8; CYKER; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; Cytokeratin-8; cytokeratin-A; DreK8; EndoA; etID33550.23; etID43142.23; etID43142.8; K2C8; K8; KERA; keratin 8; keratin 8, type II; keratin complex 2, basic, gene 8; keratin, type 2, gene 8; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8-like protein; keratin-8; KO; Krt-2.8; Krt2-8; krt8; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8; sb:cb186; type II cytokeratin A (no.8); type-II keratin Kb8; wu:fa20h05; wu:fa95h10; wu:fb96c06; zfk8; zf-K8
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov