Invitrogen™ Cytokeratin 85/86 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100851

Catalog No. PIPA5100851

Description

Antibody detects endogenous levels of total KRT85/86.

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.

Specifications

• Antigen: Cytokeratin 85/86
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KRT86
• Gene Alias: 5430421N21Rik; AA589597; AI325212; BB007925; ECTD4; hair keratin K2.10; Hair keratin K2.11; hair keratin K2.12; hard keratin, type II, 3; hard keratin, type II, 5; hard keratin, type II, 6; Hb1; HB3; Hb-3; Hb5; Hb-5; HB6; hHb3; hHb5; K83; K85; K86; keratin 83; keratin 83, type II; keratin 85; keratin 85, type II; keratin 86; keratin 86, type II; keratin complex 2, basic, gene 10; keratin complex 2, basic, gene 18; keratin protein HB6; keratin type II; keratin, hair, basic, 3; keratin, hair, basic, 5; keratin, hair, basic, 6 (monilethrix); keratin, type II cuticular Hb3; Keratin, type II cuticular Hb5; keratin, type II cuticular Hb6; Keratin-83; keratin-85; Keratin-86; Khb4; Krt2-10; Krt2-11; Krt2-18; KRT83; Krt85; KRT86; KRTHB1; KRTHB3; KRTHB5; KRTHB6; MHb4; MNX; RIKEN cDNA 5430421N21 gene; type II hair keratin; type II hair keratin Hb3; Type II hair keratin Hb5; type II hair keratin Hb6; Type-II keratin Kb23; type-II keratin Kb25; Type-II keratin Kb26
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16679, 3891, 3892, 53622
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O43790, P78386, P97861, Q9Z2T6
• Gene Symbols: KRT85, KRT86
• Immunogen: A synthesized peptide derived from human KRT85(Accession P78386), corresponding to amino acid residues R307-K357.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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