Cytokeratin, LMW Antibody (AE-1), FITC, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP233178F

Catalog No. NB005749

Description

Cytokeratin, LMW Monoclonal specifically detects Cytokeratin, LMW in Human, Mouse, Rat, Bovine, Canine, Chicken, Monkey, Rabbit, Reptile samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Cytokeratin, LMW
• Classification: Monoclonal
• Conjugate: FITC
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: KRT77
• Immunogen: Human epidermal keratin (Uniprot: Q7Z794)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit
• Isotype: IgG1 κ

• Applications: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Clone: AE-1
• Dilution: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Alias: Cytokeratin LMW, cytokeratin-1B, keratin 77, keratin, type II cytoskeletal 1b, KRT77, type-II keratin Kb39
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Test Specificity: This monoclonal antibody recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI, 48, 46, 45, and 40kDa. monoclonal antibody AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
• Content And Storage: Store at 4°C in the dark.