Cytokeratin, pan Antibody (KRTL/1077 + KRTH/1076) - IHC-Prediluted, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP248299

Catalog No. NBP248299

Description

Cytokeratin, pan Monoclonal specifically detects Cytokeratin, pan in Human, Rat samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Cytokeratin, pan
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: 10 mM PBS with 0.05% BSA with 0.05% Sodium Azide
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRTL/KRTH is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin)
• Clone: KRTL/1077 + KRTH/1076
• Dilution: Immunohistochemistry-Paraffin
• Gene Symbols: KRT1
• Immunogen: This Cytokeratin, pan Antibody (KRTL/1077 + KRTH/1076) was developed against recombinant human KRT77 and KRT76 protein.
• Quantity: 7 mL
• Research Discipline: Apoptosis, Cancer, Cell Biology, Cellular Markers, Signal Transduction
• Gene ID (Entrez): 3848
• Target Species: Human, Rat
• Form: Purified