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Cytokeratin, pan Antibody (PAN-CK (Cocktail)), FITC, Novus Biologicals™
SDP

Catalog No. NBP276425F Shop All R&D Systems Products
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NBP276425F 0.1 mL
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Catalog No. NBP276425F Supplier Novus Biologicals Supplier No. NBP276425F
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Description

Mouse Monoclonal Antibody

Cytokeratin, pan Monoclonal specifically detects Cytokeratin, pan in Human, Mouse, Rat, Bovine, Canine, Chicken, Monkey, Rabbit samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunofluorescence.

Specifications

Antigen Cytokeratin, pan
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone PAN-CK (Cocktail)
Conjugate FITC
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation PBS with 0.05% Sodium Azide
Gene Symbols KRT1
Host Species Mouse
Immunogen This Cytokeratin, pan Antibody (PAN-CK (Cocktail)) was developed against human epidermal keratin.
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Apoptosis, Cancer, Cell Biology, Cellular Markers, Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 3848
Test Specificity Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 55kDa (CK7); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 46kDa (CK17); 45kDa (CK18) and 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad-spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas.
Target Species Human, Mouse, Rat, Canine, Chicken, Monkey, Primate, Rabbit
Content And Storage Store at 4°C in the dark.
Isotype IgG κ
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