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Invitrogen™ D2HGDH Polyclonal Antibody
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Catalog No. PIPA5100063
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100 μL
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PIPA5100063 100 μL
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Catalog No. PIPA5100063 Supplier Invitrogen™ Supplier No. PA5100063
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total D2HGDH.

This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
TRUSTED_SUSTAINABILITY

Specifications

Antigen D2HGDH
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene D2HGDH
Gene Accession No. P84850, Q8CIM3, Q8N465
Gene Alias AA408776; AA408778; AI325464; D2HGD; D2HGDH; D2hgdh {ECO:0000250; D-2-hydroxyglutarate dehydrogenase; D-2-hydroxyglutarate dehydrogenase, mitochondrial; FLJ42195; LOW QUALITY PROTEIN: D-2-hydroxyglutarate dehydrogenase, mitochondrial; MGC25181; RGD1307976; UniProtKB:Q8N465}
Gene Symbols D2HGDH
Host Species Rabbit
Immunogen A synthesized peptide derived from human D2HGDH(Accession Q8N465), corresponding to amino acid residues E409-P459.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 301624, 728294, 98314
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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