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Invitrogen™ D2HGDH Polyclonal Antibody
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Catalog No. PIPA563269
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100 μL
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PIPA563269 100 μL
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Catalog No. PIPA563269 Supplier Invitrogen™ Supplier No. PA563269
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PGFAEVLQTF STCKGMLGEI LSAFEFMDAV CMQLVGRHLH LASPVQESPF YVLIETSGSN AGHDAEKLGH FLEHALGSGL VTDGTMATDQ RKVKMLWALR ERITEALSRD GYVYKYDLSL Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 85%.

This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
TRUSTED_SUSTAINABILITY

Specifications

Antigen D2HGDH
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene D2HGDH
Gene Accession No. Q8N465
Gene Alias AA408776; AA408778; AI325464; D2HGD; D2HGDH; D2hgdh {ECO:0000250; D-2-hydroxyglutarate dehydrogenase; D-2-hydroxyglutarate dehydrogenase, mitochondrial; FLJ42195; LOW QUALITY PROTEIN: D-2-hydroxyglutarate dehydrogenase, mitochondrial; MGC25181; RGD1307976; UniProtKB:Q8N465}
Gene Symbols D2HGDH
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human D2HGDH. Recombinant protein control fragment (Product #RP-98926).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 728294
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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