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Invitrogen™ D2HGDH Polyclonal Antibody
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Catalog No. PIPA595720
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100 μL
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PIPA595720 100 μL
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Catalog No. PIPA595720 Supplier Invitrogen™ Supplier No. PA595720
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GRHLHLASPV QESPFYVLIE TSGSNAGHDA EKLGHFLEHA LGSGLVTDGT MATDQRKVKM LWALRERITE ALSRDGYVYK YDLSLPVERL YDIVTDLRAR LGPHAKHVVG YGHLGDGNLH LNVTAEAFSP SLLAALEPHV YEWTAGQQGS VSAEHGVGFR KRDVLGYSKP PGALQLMQQL KALLDPKGIL NPYKTLPSQA; Positive Samples: Mouse liver, Rat heart.

This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
TRUSTED_SUSTAINABILITY

Specifications

Antigen D2HGDH
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.91 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene D2HGDH
Gene Accession No. P84850, Q8CIM3
Gene Alias AA408776; AA408778; AI325464; D2HGD; D2HGDH; D2hgdh {ECO:0000250; D-2-hydroxyglutarate dehydrogenase; D-2-hydroxyglutarate dehydrogenase, mitochondrial; FLJ42195; LOW QUALITY PROTEIN: D-2-hydroxyglutarate dehydrogenase, mitochondrial; MGC25181; RGD1307976; UniProtKB:Q8N465}
Gene Symbols D2HGDH
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 322-521 of human D2HGDH (NP_6899964).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 301624, 98314
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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