D4 Dopamine Receptor Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA528756

Catalog No. PIPA528756

Description

Recommended positive controls: HCT116. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

Specifications

• Antigen: D4 Dopamine Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DRD4
• Gene Alias: AW125663; D(2C) dopamine receptor; D(4) dopamine receptor; D4DR; D4R; D4RA; Dopamine 4 receptor; Dopamine D4 receptor; dopamine receptor 4; dopamine receptor D4; DRD4; Drd-4; seven transmembrane helix receptor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13491, 1815
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P21917, P51436
• Gene Symbols: DRD4
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human dopamine receptor D4
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov