Invitrogen™ DAAM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562993

Catalog No. PIPA562993

Description

Immunogen sequence: RKRSHHGLGF LCCFGGSDIP EINLRDNHPL QFMEFSSPIP NAEELNIRFA ELVDEL Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%.

DAAM2 is a recently identified planar cell polarity (PCP) signaling molecule implicated in the regulation of cellular polarity, convergent extension, and invasion. DAAM2 belongs to the formin homology family and contains a DAD (diaphanous autoregulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/ formin homology 3) domain. The DAAM2 protein is known to be involved in cell divison. Though the exact function of DAAM2 is yet unknown, reports suggest that it is closely related to DAAM1 and hence along with DAAM1 it may also be required in Wnt/Fz signaling and activation of Rho and in regulating cytoskeleton architecture. DAAM2 is expressed in most of tissues but the expression level ishigher in brain.

Specifications

• Antigen: DAAM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DAAM2
• Gene Alias: 2310016D11Rik; AI843643; AW557870; Daam2; Disheveled-associated activator of morphogenesis 2; dishevelled associated activator of morphogenesis 2; dishevelled-associated activator of morphogenesis 2; dJ90A20A.1; Kiaa0381; RP1-278E11.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23500
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86T65
• Gene Symbols: DAAM2
• Immunogen: Recombinant protein corresponding to Human DAAM2. Recombinant protein control fragment (Product #RP-101346).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG