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DAAM2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982236
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100 μL
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50-198-2236 100 μL
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Catalog No. 50-198-2236 Supplier Bioss Supplier No. BS12430R
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Rabbit Polyclonal Antibody

DAAM2 is a recently identified planar cell polarity (PCP) signaling molecule implicated in the regulation of cellular polarity, convergent extension, and invasion. DAAM2 belongs to the formin homology family and contains a DAD (diaphanous autoregulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/ formin homology 3) domain. The DAAM2 protein is known to be involved in cell divison. Though the exact function of DAAM2 is yet unknown, reports suggest that it is closely related to DAAM1 and hence along with DAAM1 it may also be required in Wnt/Fz signaling and activation of Rho and in regulating cytoskeleton architecture. DAAM2 is expressed in most of tissues but the expression level ishigher in brain.

Specifications

Antigen DAAM2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene DAAM2
Gene Accession No. Q86T65
Gene Alias 2310016D11Rik; AI843643; AW557870; DAAM2; Disheveled-associated activator of morphogenesis 2; dishevelled associated activator of morphogenesis 2; dishevelled-associated activator of morphogenesis 2; dJ90A20A.1; Kiaa0381; RP1-278E11.1
Gene Symbols DAAM2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human DAAM2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23500
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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